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By GlobeNewswire — Single 10 µg dose of samRNA vaccine containing Spike plus additional T cell epitopes (TCE) induced robust neutralizing antibody titers in ten healthy adults ≥ 60yrs who had received two prior doses of AstraZeneca’s COVID-19 vaccine — — samRNA vaccine elicited broad CD8+ T cell responses against conserved non-Spike SARS-CoV-2 epitopes and boosted pre-existing Spike-specific T cells — — samRNA vaccine was well-tolerated in these subjects, with no grade 3 or 4 adverse events observed — — Gritstone is expanding CORAL-BOOST to 120 subjects, potentially enabling more ra…
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